Now in the world there is a pronounced cult of the body. It’s not so bad, and when you’re surrounded by beautiful people is always nice. Especially want to reach out to them and that our world becomes a little more beautiful. And it helps to maintain health and to lead a good lifestyle. Except we are talking about the perfect man, who just like physical exercise. But the number of those who prefer a result, much higher. In the end, on his way to a perfect athletic body, which default inherent in each of us, they encounter the first problems, and immediately retreat. Blame them not, but to help them you can. It seems scientists have made another step on this way is gene therapy.
What is follistatin
That is so possible, said scientists from the Medical school at Washington University in St. Louis. Their study showed that it is possible to not only work with the genes to obtain streamlined species, but also to work, if I may say so, of a medical nature. During their research, they experimented on mice and fed them a diet high in fat.
The purpose of the experiment was figuring out how to prevent obesity and increase muscle mass in their little Guinea pig.
Throughout the study the emphasis was made on studying protein follistatin. It is produced in almost all tissues of living organisms. It was first discovered and gave him the description back in the late 80-ies of the last century. At first it was believed that it acts as a reproductive hormone, but it later emerged that his main task is to influence several cellular processes, including recovery and muscle growth.
The hormone responsible for muscle recovery
Previously conducted research of this hormone. However, then they are more related to the possibility of its effect on degenerative diseases of the muscles and the study of methods of therapy. This time the objective was to determine whether follistatin to help in the treatment of osteoarthritis by improving metabolism, reduced obesity and increased muscle mass.
The most common risk factor for osteoarthritis is obesity, – explains Gilak Farshid, author of the new study. — Excess weight prevents a person lead an active lifestyle and exercise. Because of this, it cannot make full use of physical therapy.
For the experiment we selected only the young mouse. For some time they were treated with gene therapy, the aim of which was to strengthen the production of follistatin.
As a result, scientists were able to achieve results. The farshid Gilak described them as “deep”.
In mice, there has been an improvement in health status, softened degeneration of the cartilage, reduced the level of inflammation and has been remodeling the bone.
We have found a way to use gene therapy, which will allow you to quickly build muscle. – says Gilak. Therapy has had a profound influence on mice and helped to control their weight. It can be assumed that this approach will be effective against arthritis, especially in cases of morbid obesity.
The use of gene therapy to treat people
It may seem that this is the first case where the use of follistatin been proposed for the treatment of a person, but it’s not. Already, research is underway that should help to use it in the treatment of cancer. However, the effectiveness of this method is not yet proven and to talk about its application for effective treatment of cancer while early. However, potential harm in the first phase of studies in humans have not been identified.
The farshid Gilak understands how the new method is far from being able to apply it to clinical treatment of humans. But this discovery really gives me hope that through gene therapy can treat many diseases. And also help to lead to a state of your body, if it is unable to independently engage in physical activity.
The implementation of the plan could take years, but we are optimistic about the prospects for reducing the damage to joints associated with osteoarthritis. In some cases, the new method can be used for the treatment of obesity. – Farshid concludes Gilak.