Unfortunately, despite a pretty decent level of modern medicine still the disease to cope with that doctors not. One of these conditions is Alzheimer’s disease — a serious disease characterized by gradual deterioration of memory. Complicated treatment of this disease because it is detected, typically at rather later stages. But recently, a group of American doctors found a brain region in which originates the disease. And this will greatly facilitate the diagnosis.
What is Alzheimer’s disease
As you know, Alzheimer’s is a disease characterized by the accumulation in the brain of the protein beta-amyloid. He if strongly not to go into neurophysiological detail, leading first to neuronal damage and then to their death. This provokes a number of symptoms. As a rule, in the early stages there is a violation of short-term memory, for example, the inability to recall something that happened recently. With the development of the disease takes place and loss of long term memory, and then there are violations of speech and cognitive functions, the person loses the ability to navigate the space, and then begin to deteriorate all body systems and, ultimately, the gradual loss of bodily functions leading to death.
The detection of the disease at the very beginning of this process, it would be a real breakthrough in the treatment of Alzheimer’s disease, because the sooner the disease is determined, the better the prognosis has in the treatment of this process. And, it seems that a group of researchers from the Massachusetts Institute of technology (MIT) managed to find out where this disease arises. About such discoveries we often write on our site, so we recommend you subscribe to our Telegram channel to not to miss anything.
During a series of experiments on laboratory mice revealed that the accumulation of amyloid plaques starts in the mastoid body. Mastoid bodies are two small, rounded education, which lies at the base of the hypothalamus directly behind the pituitary gland in the brain.
Findings indicate that changes in the human brain during the development of Alzheimer’s disease occur in the same way, say the authors. Understanding of the areas of origin of the pathological process will allow to develop new therapeutic methods for the treatment of the disease, and on his identification.
Thus on the simple assumption, scientists have not stopped and checked their hypotheses. Has long been known that the density of amyloid plaques is higher in those areas of the brain where the disease has been around longer. And, accordingly, the plaques are much smaller in the newly affected parts of the Central nervous system. Based on this assumption, and also that in laboratory mice the accumulation of amyloid began in the mastoid body, the scientists analyzed the tissues of the human brain. It turned out that in this area the number of abnormal protein really extremely high.
Now the researchers hope to develop methods for diagnosis and detection of Alzheimer’s disease at an early stage, because now they are, roughly speaking, “do you know where to look.” In parallel with the “precise diagnosis” will be conducted to test hypotheses about the origin of the disease in humans. It will be possible to verify the obtained data.