An experimental new approach may help in the treatment of colds

Autumn — Golden time. And still love her very much pharmaceutical companies and manufacturers peplomycin. And all because a cold at this time of year is not difficult. In our society a cold is not customary to pay close attention. As a rule, most cold continue to go to work and attend educational institutions. Thus, they spread the infection. However, no matter how harmless you seemed cold, scientists are not the first year struggling with the problems associated with her treatment. Fighting a cold is a huge health problem. Scientists recently stated that it had discovered a new way to defeat her.

Fall should be especially attentive to itself

What is the flu?

A cold is a generalized term that unites a range of symptoms including a disorder of the upper respiratory tract. In most cases, cause the common cold rhinoviruses the Rhinovirus genus. For them characteristic symptoms such as copious nasal discharge, sore throat and slight fever. Actually types of rhinoviruses there are no less than 160. However, the biggest problem is that these viruses mutate very quickly and often develop resistance to the drugs. Sometimes they become so resourceful, learning to hide from the immune system.

So rhinovirus looks like under a microscope

Due to the huge number of recurring mutations, to pick up cold medicine is incredibly difficult. That’s why experts say that most of the tools sold as a cold medicine do not work. According to doctors, the flu is like a drug, and without it in about seven days. However, the main danger of a cold are complications. If you neglect your health, the common cold can result in serious consequences to health.

How to beat a cold?

All of the above gave scientists the idea that the treatment is not very cold, and its owner. That is on you. Scientists are thinking about how to make the body unfavorable for viruses. Due to the fact that particular virus does not have all the necessary means to copy, its spread depends on the infection of other cells and steal some of the internal components of cells. Recently a team of scientists from Stanford and California universities have found one of the components that affect the reproduction of viruses.

The scientists started with human cells, using genome editing. Experts would in turn “disable” of the user that will stimulate some genes. Subsequently, the modified cells are deliberately infected by a number of enteroviruses, including rhinoviruses that cause the common cold, and more dangerous viruses that are closely related to polio and can cause paralysis. As a result, scientists have achieved the desired viruses embedded in the edited cells could not reproduce. According to experts, by editing they are “turned off” the production in the cells a protein complex called methyltransferase SETD3.

In fact, not everyone can easily tolerate the cold

Then scientists bred genetically modified mice that have been absolutely unable to produce this protein. In an interview with BBC News, one of the study’s authors, Jan Garett said that the absence of this gene completely protected mice from viral infection. The results, published in the journal Nature Microbiology, showed that genetically modified mice remained healthy throughout life despite the lack of a protein methyltransferase SETD3.

When we get the cure?

For the development of drugs, scientists do not need genetically modified people. The plan is not to find a cure that will be able to suppress the protein and to protect from viruses. According to Professor Caretta from Stanford University, it is necessary to remove the desired protein and all viruses — the rhinoviruses and enteroviruses there will be no chance.

Advertisements